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Gene Information

Gene symbol: HIF1A

Gene name: hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

HGNC ID: 4910

Synonyms: MOP1, HIF-1alpha, PASD8, HIF1, bHLHe78

Related Genes

# Gene Symbol Number of hits
1 ARNT 1 hits
2 CXCR4 1 hits
3 EPAS1 1 hits
4 JUND 1 hits
5 VEGFA 1 hits

Related Sentences

# PMID Sentence
1 12660327 In response to hypoxia, stabilized HIF-1alpha and HIF-2alpha proteins bind HIF-1beta and initiate expression of genes that alleviate hypoxic stress, including those promoting neovascularization.
2 12660327 Both HIF-1 and HIF-2 heterodimers were identified in newborn kidney lysates by immunoprecipitation with HIF-1alpha, HIF-2alpha, and HIF-1beta antibodies and Western blots.
3 16374431 The HIF-target gene VEGF colocalized with HIF-1alpha protein in glomeruli and medullary collecting ducts.
4 20019191 This CXCR4 positivity was associated with nuclear localization of HIF1alpha only in podocytes of NSC, indicating transcriptional activity of HIF.
5 21640331 Accordingly, small-interfering RNA-mediated JUND knockdown in conditionally immortalized human podocyte cell lines led to increased VEGFA and HIF1A expression.