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Gene Information
Gene symbol: HIF1A
Gene name: hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HGNC ID: 4910
Synonyms: MOP1, HIF-1alpha, PASD8, HIF1, bHLHe78
Related Genes
Related Sentences
# |
PMID |
Sentence |
1 |
12660327
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In response to hypoxia, stabilized HIF-1alpha and HIF-2alpha proteins bind HIF-1beta and initiate expression of genes that alleviate hypoxic stress, including those promoting neovascularization.
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2 |
12660327
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Both HIF-1 and HIF-2 heterodimers were identified in newborn kidney lysates by immunoprecipitation with HIF-1alpha, HIF-2alpha, and HIF-1beta antibodies and Western blots.
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3 |
16374431
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The HIF-target gene VEGF colocalized with HIF-1alpha protein in glomeruli and medullary collecting ducts.
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4 |
20019191
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This CXCR4 positivity was associated with nuclear localization of HIF1alpha only in podocytes of NSC, indicating transcriptional activity of HIF.
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5 |
21640331
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Accordingly, small-interfering RNA-mediated JUND knockdown in conditionally immortalized human podocyte cell lines led to increased VEGFA and HIF1A expression.
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