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Gene Information
Gene symbol: IL13
Gene name: interleukin 13
HGNC ID: 5973
Synonyms: P600, IL-13, ALRH, BHR1, MGC116786, MGC116788, MGC116789
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD80 | 1 hits |
| 2 | NPHS1 | 1 hits |
| 3 | NPHS2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 17429054 | Immunofluorescence staining intensity was reduced for nephrin, podocin, and dystroglycan but increased for B7-1 and IL-4Ralpha in IL-13-transfected rats compared with controls. |
| 2 | 17429054 | In conclusion, these results suggest that IL-13 overexpression in the rat could lead to podocyte injury with downregulation of nephrin, podocin, and dystroglycan and a concurrent upregulation of B7-1 in the glomeruli, inducing a minimal change-like nephropathy that is characterized by increased proteinuria, hypoalbuminemia, hypercholesterolemia, and fusion of podocyte foot processes. |
| 3 | 19556042 | Recent studies suggest that interleukin 13, a known stimulator of IgE response, may mediate proteinuria in patients with minimal change disease because of its ability to directly induce CD80 expression on the podocyte. |
| 4 | 21839364 | Interleukin-13 or microbial products via Toll-like receptors could be factors that induce CD80 expression on podocytes. |