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Gene Information
Gene symbol: INSR
Gene name: insulin receptor
HGNC ID: 6091
Synonyms: CD220
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AKT1 | 1 hits |
| 2 | IGF1 | 1 hits |
| 3 | MAPK3 | 1 hits |
| 4 | SLC2A4 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 15780083 | IGF-1 stimulation resulted in the formation of the insulin receptor substrate (IRS)-1-p85 complex, an increase in PI3 kinase activity, and activation of protein kinase B (AKT/PKB) and the bcl-2 family member bad. |
| 2 | 19556298 | At the protein level, phosphorylation of the insulin receptor, IRS1 and PKB was reduced and there was impaired translocation of GLUT4 to the cell surface. |
| 3 | 20375985 | Furthermore, visfatin induced tyrosine phosphorylation of the insulin receptor, activated downstream insulin signaling pathways such as Erk-1, Akt, and p38 MAPK, and markedly increased the levels of TGFbeta1, PAI-1, type I collagen, and MCP-1 in both renal cells. |