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Gene Information
Gene symbol: JUND
Gene name: jun D proto-oncogene
HGNC ID: 6206
Synonyms: AP-1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CXCL12 | 1 hits |
| 2 | CXCR4 | 1 hits |
| 3 | HIF1A | 1 hits |
| 4 | VEGFA | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21640331 | Furthermore, cultured glomeruli from Jund(-/-) mice showed relatively increased expression of vascular endothelial growth factor A (Vegfa), Cxcr4, and Cxcl12, well-known HIF target genes. |
| 2 | 21640331 | Accordingly, small-interfering RNA-mediated JUND knockdown in conditionally immortalized human podocyte cell lines led to increased VEGFA and HIF1A expression. |
| 3 | 21640331 | Our findings suggest that deficiency of Jund may cause increased oxidative stress in podocytes, leading to altered VEGFA expression and subsequent glomerular injury in Crgn. |