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Gene Information
Gene symbol: KDR
Gene name: kinase insert domain receptor (a type III receptor tyrosine kinase)
HGNC ID: 6307
Synonyms: FLK1, VEGFR, VEGFR2, CD309
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
22038228
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The aim of the present work was to analyze the possible relation between VEGF-C and VEGF receptor (VEGFR)-2 expressions at electron microscopy level in different INS cases.
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2 |
22038228
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VEGF-C over-expression in these cases was followed by downregulation of VEGFR-2.
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3 |
16239266
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The VEGF-induced elevation of LpA/Vi was blocked by the selective VEGF-R2 inhibitor ZM323881.
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4 |
16436677
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Additionally, VEGFR2 was constitutively phosphorylated in the liver, lung, adipose, and kidney in vivo, providing evidence consistent with a role for VEGF in adult tissues.
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5 |
20688931
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Unlike cell culture models, enhanced expression of VEGF by podocytes in vivo caused foot process fusion and alterations in slit diaphragm-associated proteins; however, inhibition of VEGFR-2 could not rescue this defect.
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6 |
12620928
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Normal human podocytes are also known to express neuropilin-1, VEGF, and are VEGF-R2 negative.
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7 |
16597608
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Differentiated podocytes expressed eightfold higher VEGFR2 mRNA levels than undifferentiated podocytes, whereas VEGFR1, sVEGFR1, NP1, and NP2 mRNA levels were similar.
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8 |
16597608
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VEGF(165) induced a twofold increase in VEGFR2 mRNA and protein levels, whereas VEGFR1, sVEGFR1, NP1, and NP2 mRNA levels remained unchanged.
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9 |
16597608
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VEGF(165) induced VEGFR2 phosphorylation.
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10 |
19828679
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We demonstrated that ablation of VEGF-A or VEGF-C as well as treatment with bevacizumab or a VEGFR-2/-3 tyrosine kinase inhibitor led to reduced podocyte survival.
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11 |
21937443
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We previously showed that in vivo nephrin associates with VEGF receptor-2 (VEGFR2), the signaling receptor for VEGF-A.
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