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Gene Information
Gene symbol: MAPK14
Gene name: mitogen-activated protein kinase 14
HGNC ID: 6876
Synonyms: PRKM14, p38, Mxi2, PRKM15
Related Genes
Related Sentences
# |
PMID |
Sentence |
1 |
12683421
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Decreased extracellular chloride increases COX-2 expression in cultured cTALH, an effect mediated by increased p38 MAP kinase activity and, in vivo, a sodium-deficient diet increases expression of activated p38 in MD/cTALH.
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2 |
16380497
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Increased extracellular glucose (30 mmol/l) rapidly stimulated generation of intracellular reactive oxygen species (ROS) through NADPH oxidase and mitochondrial pathways and led to activation of proapoptotic p38 mitogen-activated protein kinase and caspase 3 and to apoptosis of conditionally immortalized podocytes in vitro.
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3 |
16514436
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Furthermore, TNFalpha and IL-18 phosphorylated neutrophil p38 mitogen-activated protein kinase (MAPK), but IL-18-mediated p38 MAPK phosphorylation was unaffected by anti-TNFalpha antibody.
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4 |
16514436
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The p38 MAPK inhibitor, SB20358, reduced IL-18-primed, ANCA-induced superoxide production in a concentration-dependent manner.
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