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Gene Information

Gene symbol: MAPK14

Gene name: mitogen-activated protein kinase 14

HGNC ID: 6876

Synonyms: PRKM14, p38, Mxi2, PRKM15

Related Genes

# Gene Symbol Number of hits
1 MAPK1 1 hits
2 NOX5 1 hits
3 PTGS2 1 hits
4 TNF 1 hits

Related Sentences

# PMID Sentence
1 12683421 Decreased extracellular chloride increases COX-2 expression in cultured cTALH, an effect mediated by increased p38 MAP kinase activity and, in vivo, a sodium-deficient diet increases expression of activated p38 in MD/cTALH.
2 16380497 Increased extracellular glucose (30 mmol/l) rapidly stimulated generation of intracellular reactive oxygen species (ROS) through NADPH oxidase and mitochondrial pathways and led to activation of proapoptotic p38 mitogen-activated protein kinase and caspase 3 and to apoptosis of conditionally immortalized podocytes in vitro.
3 16514436 Furthermore, TNFalpha and IL-18 phosphorylated neutrophil p38 mitogen-activated protein kinase (MAPK), but IL-18-mediated p38 MAPK phosphorylation was unaffected by anti-TNFalpha antibody.
4 16514436 The p38 MAPK inhibitor, SB20358, reduced IL-18-primed, ANCA-induced superoxide production in a concentration-dependent manner.