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Gene Information
Gene symbol: NR3C2
Gene name: nuclear receptor subfamily 3, group C, member 2
HGNC ID: 7979
Synonyms: MR
Related Genes
Related Sentences
# |
PMID |
Sentence |
1 |
19261739
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Recent evidence suggests that mineralocorticoid receptor (MR) antagonism has beneficial effects on tissue oxidative stress and insulin metabolic signaling as well as reducing proteinuria.
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2 |
21177830
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Compared with Zucker lean, ZO controls exhibited increased proteinuria and ?-glutamyl transpeptidase, reductions in systemic insulin sensitivity in association with increased renal renin, (pro)renin receptor, angiotensin II type 1 receptor, and mineralocorticoid receptor immunostaining, oxidative stress, and glomerular tubular structural abnormalities that were substantially improved with in vivo nebivolol treatment.
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3 |
21209008
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Furthermore, the VDR agonist also prevents the activation of the renin-angiotensin-aldosterone system including the angiotensin II type 1 receptor and the mineralocorticoid receptor.
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