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Gene Information

Gene symbol: NR3C2

Gene name: nuclear receptor subfamily 3, group C, member 2

HGNC ID: 7979

Synonyms: MR

Related Genes

# Gene Symbol Number of hits
1 INS 1 hits
2 VDR 1 hits

Related Sentences

# PMID Sentence
1 19261739 Recent evidence suggests that mineralocorticoid receptor (MR) antagonism has beneficial effects on tissue oxidative stress and insulin metabolic signaling as well as reducing proteinuria.
2 21177830 Compared with Zucker lean, ZO controls exhibited increased proteinuria and ?-glutamyl transpeptidase, reductions in systemic insulin sensitivity in association with increased renal renin, (pro)renin receptor, angiotensin II type 1 receptor, and mineralocorticoid receptor immunostaining, oxidative stress, and glomerular tubular structural abnormalities that were substantially improved with in vivo nebivolol treatment.
3 21209008 Furthermore, the VDR agonist also prevents the activation of the renin-angiotensin-aldosterone system including the angiotensin II type 1 receptor and the mineralocorticoid receptor.