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Gene Information
Gene symbol: NTRK1
Gene name: neurotrophic tyrosine kinase, receptor, type 1
HGNC ID: 8031
Synonyms: TRK, TRKA, MTC
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CTGF | 1 hits |
| 2 | TGFB1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 19214781 | CTGF is also able to interact with receptors on cells, including integrins, tyrosine receptor kinase A (TrkA), low density lipoprotein receptor-related protein (LRP) and heparan sulphate proteoglycans. |
| 2 | 19214781 | It can promote TGF-beta signalling by binding directly to the growth factor, promoting its interaction with the TGF-beta receptor; by triggering intracellular signalling on binding the TrkA receptor, which leads to the transcriptional repression of Smad7, an inhibitor of the TGF-beta signalling pathway; and by binding to BMP-7 whose own signalling pathway opposing TGF-beta is inhibited, leading to enhanced TGF-beta signalling. |