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Gene Information
Gene symbol: OSGEP
Gene name: O-sialoglycoprotein endopeptidase
HGNC ID: 18028
Synonyms: PRSMG1, GCPL1, OSGEP1, KAE1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ILK | 1 hits |
| 2 | NPHS1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20576809 | Here, we report that nephrin interacts with the bicarbonate/chloride transporter kidney anion exchanger 1 (kAE1), detected by yeast two-hybrid assay and confirmed by immunoprecipitation and co-localization studies. |
| 2 | 20576809 | We could not detect endogenous kAE1 expression in NPHS1(FinMaj) podocytes in primary culture, but heterologous re-introduction of wild-type nephrin into these podocytes rescued kAE1 expression. |
| 3 | 20576809 | In kidneys of Ae1(-/-) mice, nephrin abundance was normal but its distribution was altered along with the reported kAE1-binding protein integrin-linked kinase (ILK). |
| 4 | 20576809 | These data suggest that the podocyte protein kAE1 interacts with nephrin and ILK to maintain the structure and function of the glomerular basement membrane. |