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Gene Information
Gene symbol: PIK3R1
Gene name: phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
HGNC ID: 8979
Synonyms: GRB1, p85-ALPHA, p85
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AKT1 | 1 hits |
| 2 | CD2AP | 1 hits |
| 3 | NPHS1 | 1 hits |
| 4 | NPHS2 | 1 hits |
| 5 | PIK3CA | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 12832477 | We demonstrate that both nephrin and CD2AP interact with the p85 regulatory subunit of phosphoinositide 3-OH kinase (PI3K) in vivo, recruit PI3K to the plasma membrane, and, together with podocin, stimulate PI3K-dependent AKT signaling in podocytes. |
| 2 | 19679673 | We found that the C-terminal region of CD2AP interacts directly with the cytoplasmic tail of the TGF-beta receptor type I (TbetaRI) in a kinase-dependent manner and that the interaction between the TbetaRI and the p85 subunit of PI3K requires CD2AP. |
| 3 | 20472933 | This Nephrin-induced cofilin activation required a direct interaction between Nephrin and the p85 subunit of phosphatidylinositol 3-kinase. |