Ignet
Search (e.g., vaccine, IFNG): Help
About
Home
Introduction
Statistics
Programs
Dignet
Gene
GenePair
Help & Docs
Documents
Help
FAQs
Links
Acknowledge
Disclaimer
Contact Us
UM Logo

UMMS Logo

UMMS Logo

Gene Information

Gene symbol: PRKAA2

Gene name: protein kinase, AMP-activated, alpha 2 catalytic subunit

HGNC ID: 9377

Synonyms: AMPK, AMPKa2

Related Genes

# Gene Symbol Number of hits
1 ADIPOQ 1 hits
2 ALB 1 hits
3 NOX5 1 hits

Related Sentences

# PMID Sentence
1 18431508 In cultured podocytes, adiponectin administration was associated with increased activity of AMPK, and both adiponectin and AMPK activation reduced podocyte permeability to albumin and podocyte dysfunction, as evidenced by zona occludens-1 translocation to the membrane.
2 18431508 These effects seemed to be caused by reduction of oxidative stress, as adiponectin and AMPK activation both reduced protein levels of the NADPH oxidase Nox4 in podocytes.
3 18431508 Ad(-/-) mice treated with adiponectin exhibited normalization of albuminuria, improvement of podocyte foot process effacement, increased glomerular AMPK activation, and reduced urinary and glomerular markers of oxidant stress.