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Gene Information
Gene symbol: PTPRO
Gene name: protein tyrosine phosphatase, receptor type, O
HGNC ID: 9678
Synonyms: PTPU2, GLEPP1, PTP-U2, PTP-oc, NPHS6
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ACTN4 | 1 hits |
| 2 | MAGI1 | 1 hits |
| 3 | MCKD1 | 1 hits |
| 4 | NPHS1 | 1 hits |
| 5 | SYNPO | 1 hits |
| 6 | TGFB1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21997392 | Compared with normal glomeruli, fewer cells stained for APOL1 in FSGS and HIVAN glomeruli, even when expression of the podocyte markers GLEPP1 and synaptopodin appeared normal. |
| 2 | 11274227 | Immunofluorescence studies of adult kidney revealed that MAGI-1 is expressed in the glomerulus of the kidney, in a manner that parallels the expression of the podocyte-specific protein glomerular epithelial protein 1. |
| 3 | 11793093 | We therefore analyzed kidney tissue from normal children (n=3), children with congenital nephrotic syndrome of the Finnish type (CNF, n=3), minimal change disease (MCD, n=3), focal segmental glomerulosclerosis (FSGS, n=3), and Galloway-Mowat syndrome (n=4) by immunohistochemistry for expression of synaptopodin, GLEPP1, intracellular domain of nephrin (nephrin-I), and extracellular domain of nephrin (nephrin-E). |
| 4 | 11793093 | Nephrin was absent, and synaptopodin and GLEPP1 expression were decreased in CNF. |
| 5 | 14531804 | In the cases of FSGS, the expression levels of TGF-beta 1, TSP-1, and TGF-betaIIR proteins and mRNAs and phosphorylated Smad2/Smad3 were significantly increased, particularly in the GEC of the sclerotic segments, wherein WT-1 and GLEPP-1 were not detected. |