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Gene Information
Gene symbol: SDK1
Gene name: sidekick cell adhesion molecule 1
HGNC ID: 19307
Synonyms: FLJ31425
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ACTN4 | 1 hits |
| 2 | CTNNB1 | 1 hits |
| 3 | MAGI1 | 1 hits |
| 4 | NPHS1 | 1 hits |
| 5 | SYNPO | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20562105 | We also show that sdk-1 associates with the slit diaphragm linker protein MAGI-1, which is already known to interact with several critical podocyte proteins including synaptopodin, alpha-actinin-4, nephrin, JAM4, and beta-catenin. |
| 2 | 20562105 | Furthermore, a truncated version of sdk-1 that is unable to bind to MAGI-1 does not induce podocyte dysfunction when overexpressed. |
| 3 | 20562105 | We conclude that the up-regulation of sdk-1 in podocytes is an important pathogenic factor in FSGS and that the mechanism involves disruption of the actin cytoskeleton possibly via alterations in MAGI-1 function. |