Ignet

Gene symbol: SERPINE1

Gene name: serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

HGNC ID: 8583

Synonyms: PAI

Related Genes

Related Sentences

#	PMID	Sentence
1	20375985	Furthermore, visfatin induced tyrosine phosphorylation of the insulin receptor, activated downstream insulin signaling pathways such as Erk-1, Akt, and p38 MAPK, and markedly increased the levels of TGFbeta1, PAI-1, type I collagen, and MCP-1 in both renal cells.
2	21832980	In vivo, ectopic expression of TGF-?1 induced Wnt1 expression, activated ?-catenin, and upregulated Wnt target genes such as Snail1, MMP-7, MMP-9, desmin, Fsp1, and PAI-1 in mouse glomeruli, leading to podocyte injury and albuminuria.