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Gene Information
Gene symbol: SMAD2
Gene name: SMAD family member 2
HGNC ID: 6768
Synonyms: MADR2, JV18-1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AGT | 1 hits |
| 2 | CD2AP | 1 hits |
| 3 | COL1A1 | 1 hits |
| 4 | MMP9 | 1 hits |
| 5 | TGFB1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 15840669 | The expression of alpha3(IV) collagen was influenced by the TGF-beta system, but AngII did not increase the podocyte's production of TGF-beta1 ligand; rather, it increased the expression of the TGF-beta type II receptor and activated the TGF-beta signalling system through Smad2. |
| 2 | 16301820 | However, blockade of Smad2 signaling pathway by Staurosporine did not affect the TGFbeta1-stimulated secretion of MMP-9, whereas inhibition of activation of ERK1/2 by PD98059 abolished TGFbeta1-stimulated secretion of MMP-9 and expression of MMP-9 mRNA. |
| 3 | 19679673 | Here, we report that CD2AP-dependent early activation of the antiapoptotic PI3K/AKT pathway does not require TGF-beta receptor-regulated Smad2 and Smad3. |