Ignet

Gene symbol: SMAD7

Gene name: SMAD family member 7

HGNC ID: 6773

Related Genes

#	Gene Symbol	Number of hits
1	TGFB1	1 hits

Related Sentences

#	PMID	Sentence
1	19214781	It can promote TGF-beta signalling by binding directly to the growth factor, promoting its interaction with the TGF-beta receptor; by triggering intracellular signalling on binding the TrkA receptor, which leads to the transcriptional repression of Smad7, an inhibitor of the TGF-beta signalling pathway; and by binding to BMP-7 whose own signalling pathway opposing TGF-beta is inhibited, leading to enhanced TGF-beta signalling.