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Gene Information
Gene symbol: SREBF1
Gene name: sterol regulatory element binding transcription factor 1
HGNC ID: 11289
Synonyms: SREBP1, bHLHd1, SREBP-1c
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | INS | 1 hits |
| 2 | NR1H4 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 19776172 | In the current study, we have determined a key role of the farnesoid X receptor (FXR) in modulating renal SREBP-1 activity, glomerular lesions, and proteinuria. |
| 2 | 21209008 | Diet-induced obesity (DIO) and insulin resistance in mice are associated with proteinuria, renal mesangial expansion, accumulation of extracellular matrix proteins, and activation of oxidative stress, proinflammatory cytokines, profibrotic growth factors, and the sterol regulatory element binding proteins, SREBP-1 and SREBP-2, that mediate increases in fatty acid and cholesterol synthesis. |