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Gene Information
Gene symbol: TEK
Gene name: TEK tyrosine kinase, endothelial
HGNC ID: 11724
Synonyms: TIE2, TIE-2, VMCM1, CD202b
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ANGPT1 | 1 hits |
| 2 | ANGPT2 | 1 hits |
| 3 | FLT1 | 1 hits |
| 4 | VEGFA | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 11261688 | Angiopoietin-1 (Ang-1) is a secreted growth factor which binds to and activates the Tie-2 receptor tyrosine kinase. |
| 2 | 17059890 | Podocalyxin expression in leukemic blasts was coupled with the concomitant expression of VEGF-R1, -R2, -R3 and Tie-2, the capacity to release VEGF-A and angiopoietin1 and the ability to differentiate into endothelial cells under appropriate culture conditions. |
| 3 | 17625119 | Angiopoietin-2 (Ang-2) modulates embryonic vascular differentiation primarily by inhibiting the antiapoptotic effects of Ang-1 on endothelia that express the Tie-2 receptor. |
| 4 | 17667850 | PAN mice also had significantly decreased Flk-1 and Tie2 mRNA expression and increased angiopoitein-1 (Ang-1) expression, without change in vascular endothelial growth factor (VEGF) at 2 dpp versus NS. |
| 5 | 18272601 | Protein expression of ANG1 and ANG2 was confined to podocytes and that of Tie-2 to endothelial cells. |
| 6 | 18272601 | At day 12 of anti-Thy1.1 GN when capillary restoration was nearly completed, ANG1 and ANG2 gene expression returned to basal levels, whereas Tie-2 expression was still high. |