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Gene Information
Gene symbol: TENC1
Gene name: tensin like C1 domain containing phosphatase (tensin 2)
HGNC ID: 19737
Synonyms: KIAA1075, C1-TEN, TNS2
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | NPHS1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 19129671 | Using tensin2-deficient mice (ICGN/Oa strain), we provide evidence that tensin2 is important for glomerular nephrin expression in vivo. |
| 2 | 19129671 | In heterozygous mice with a single mutated tensin2 allele, nephrin expression was maintained, while albuminuria was not observed. |
| 3 | 19129671 | In contrast, nephrin expression was impaired, especially in the central zones of glomeruli of homozygous mice (with double mutated tensin2 alleles), even at one week after birth. |
| 4 | 19129671 | Therefore, we suggested that tensin2 is involved in expression and extension of nephrin, while tensin2 deficiency may result in proteinuria, associated with the loss of slit integrity. |