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Gene Information
Gene symbol: TJP1
Gene name: tight junction protein 1
HGNC ID: 11827
Synonyms: ZO-1, MGC133289, DKFZp686M05161
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ADD2 | 1 hits |
| 2 | CNR1 | 1 hits |
| 3 | EGFR | 1 hits |
| 4 | FAT | 1 hits |
| 5 | ILK | 1 hits |
| 6 | LMX1B | 1 hits |
| 7 | NPHS1 | 1 hits |
| 8 | PIK3CA | 1 hits |
| 9 | SYNPO | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 11106563 | We studied the developmental expression of nephrin, ZO-1 and P-cadherin in normal fetal kidneys and in NPHS1 kidneys. |
| 2 | 11106563 | Fetal NPHS1 kidneys with Fin-major/Fin-major genotype did not express nephrin, whereas the expression of ZO-1 and P-cadherin was comparable to that of control kidneys. |
| 3 | 11231355 | Furthermore, the double-label immunogold technique with ultrathin cryosections demonstrated that gold particles for FAT cytoplasmic domain were located at the base of slit diaphragms labeled by mAb 5-1-6 and that the cytoplasmic domain of FAT colocalized with ZO-1, a cytoplasmic component associated with slit diaphragms. |
| 4 | 11956244 | Using antibodies to podocyte proteins important for podocyte function, we found that Lmx1b(-/-) podocytes express near-normal levels of nephrin, synaptopodin, ZO-1, alpha3 integrin, and GBM laminins. |
| 5 | 16155592 | Biochemical studies reveal that nephrin directly binds to the middle PDZ domains of MAGI-1 through its carboxyl terminus but does not bind to ZO-1. |
| 6 | 20566668 | We propose that ZO-1 redistribution is an important element of BK-induced permeability change and the signaling events involved in ZO-1 rearrangement include transactivation of the EGFR via ADAM17 activation and ER shedding. |
| 7 | 20505657 | Ectopic expression of ILK in podocytes decreased levels of the epithelial markers nephrin and ZO-1, induced mesenchymal markers such as desmin, fibronectin, matrix metalloproteinase-9 (MMP-9), and alpha-smooth muscle actin (alpha-SMA), promoted cell migration, and increased the paracellular albumin flux across podocyte monolayers. |
| 8 | 19838659 | The introgression of polymorphic MHS beta-adducin locus into MNS (Add2, 529R) rats was associated with an early reduction of podocyte protein expression (nephrin, synaptopodin, alpha-actinin, ZO-1, podocin, Fyn), followed by severe glomerular and interstitial lesions and increased urinary protein excretion. |
| 9 | 20068137 | Expression of nephrin, podocin, synaptopodin, and zonula occludens-1 (ZO-1) was assessed by immunofluorescence and real-time PCR. |
| 10 | 20068137 | Furthermore, CB1 blockade completely prevented diabetes-induced downregulation of nephrin, podocin, and ZO-1. |
| 11 | 20054520 | In addition, LY294002, a PI3-K inhibitor, could prevent the quantitative and distributional changes of ZO-1 and RAGE and the increased permeability induced by HG and AGE. |