Gene Information
Gene symbol: TNFSF12
Gene name: tumor necrosis factor (ligand) superfamily, member 12
HGNC ID: 11927
Synonyms: TWEAK, DR3LG, APO3L
Related Genes
Related Sentences
# |
PMID |
Sentence |
1 |
20953353
|
While TNF only activates canonical NF-kappaB signaling, TWEAK promotes both canonical and noncanonical NF-kappaB activation in tubular cells, regulating different inflammatory responses.
|
2 |
20953353
|
TWEAK promotes the secretion of MCP-1 and RANTES through NF-kappaB RelA-containing complexes and upregulates CCl21 and CCL19 expression through NF-kappaB inducing kinase (NIK-) dependent RelB/NF-kappaB2 complexes.
|