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Gene Information

Gene symbol: CD59

Gene name: CD59 molecule, complement regulatory protein

HGNC ID: 1689

Synonyms: 16.3A5, EJ16, EJ30, EL32, G344, p18-20

Related Genes

#	Gene Symbol	Number of hits
1	AHSA1	1 hits
2	FDX1	1 hits
3	PIK3CA	1 hits

Related Sentences

#	PMID	Sentence
1	21215189	And then, the effects of P38MAPK, PI-3K and ERK1/2 pathway inhibitors (SB203580, LY294002, U0126) and DMSO on CD59 and Crry expression were respectively detected by flow cytometry.
2	21215189	Compared with group B, CD59 and Crry expression in group Ad was not significantly different (P values for both > 0.05), but CD59 and Crry protein expression in Ad-X group was significantly higher than that in groups B and Ad (P values for both < 0.005); CD59 and Crry gene expression in group Ad was not significantly different from that in group B (P values for both > 0.05).
3	21215189	P38 pathway inhibition resulted in significantly lower CD59 and Crry expression than Ad-X group (P values for all < 0.005), but PI-3K, ERK1/2 pathway inhibitors and DMSO had no significant effect on the expression of CD59 and Crry (P values for all > 0.05).
4	21215189	HBx can up-regulate CD59 and Crry expression in podocytes through activating P38 pathway, resulting in decreased complement activation, which may facilitate latent HBV infection in podocytes and play a role in development of hepatitis B virus associated glomerulonephritis (HBV-GN).