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Gene Information
Gene symbol: CDC42
Gene name: cell division cycle 42 (GTP binding protein, 25kDa)
HGNC ID: 1736
Synonyms: G25K, CDC42Hs
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | BAIAP2 | 1 hits |
| 2 | ENAH | 1 hits |
| 3 | NRP1 | 1 hits |
| 4 | PLAUR | 1 hits |
| 5 | SYNPO | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 17569780 | Here we show that synaptopodin directly binds to IRSp53 and suppresses Cdc42:IRSp53:Mena-initiated filopodia formation by blocking the binding of Cdc42 and Mena to IRSp53. |
| 2 | 17569780 | The identification of synaptopodin as an inhibitor of Cdc42:IRSp53:Mena signaling defines a novel antiproteinuric signaling pathway and offers new targets for the development of antiproteinuric therapeutic modalities. |
| 3 | 18084301 | Mechanistically, uPAR is required to activate alphavbeta3 integrin in podocytes, promoting cell motility and activation of the small GTPases Cdc42 and Rac1. |
| 4 | 21734098 | Analysis of RhoA family GTPase activity demonstrated that treatment with AGE-BSA or NRP1 depletion inhibited as well the activation of the Rac-1 and Cdc42 but did not affect RhoA activity. |