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Gene Information
Gene symbol: COL4A4
Gene name: collagen, type IV, alpha 4
HGNC ID: 2206
Synonyms: CA44
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AGRN | 1 hits |
| 2 | AMMECR1 | 1 hits |
| 3 | COL1A1 | 1 hits |
| 4 | TIMP1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16196291 | It is concluded that calcium dobesilate can improve diabetic nephropathy by inhibiting the over- accumulation of collagen IV and calcium dobesilate may also contribute to diabetes by inhibiting the expression of TIMP1. |
| 2 | 17768702 | Agrin expression was significantly altered in diabetic versus non-diabetic MHS animals, whereas collagen I was expressed only in diabetic MHS rats and collagen IV content did not change significantly between the two groups. |
| 3 | 21152865 | Furthermore, both treatments failed to influence TGF-ß1 and MCP-1 secretion and to modulate RAGE and collagen IV expression. |
| 4 | 21519194 | However, collagen IV mutation, which causes Alport syndrome and ESRD in humans, leads to gradual damage to the GBM that eventually leads to albuminuria and renal failure. |