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Gene Information

Gene symbol: NTRK1

Gene name: neurotrophic tyrosine kinase, receptor, type 1

HGNC ID: 8031

Synonyms: TRK, TRKA, MTC

Related Genes

# Gene Symbol Number of hits
1 CTGF 1 hits
2 TGFB1 1 hits

Related Sentences

# PMID Sentence
1 19214781 CTGF is also able to interact with receptors on cells, including integrins, tyrosine receptor kinase A (TrkA), low density lipoprotein receptor-related protein (LRP) and heparan sulphate proteoglycans.
2 19214781 It can promote TGF-beta signalling by binding directly to the growth factor, promoting its interaction with the TGF-beta receptor; by triggering intracellular signalling on binding the TrkA receptor, which leads to the transcriptional repression of Smad7, an inhibitor of the TGF-beta signalling pathway; and by binding to BMP-7 whose own signalling pathway opposing TGF-beta is inhibited, leading to enhanced TGF-beta signalling.