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Gene Information

Gene symbol: PIK3R1

Gene name: phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

HGNC ID: 8979

Synonyms: GRB1, p85-ALPHA, p85

Related Genes

# Gene Symbol Number of hits
1 AKT1 1 hits
2 CD2AP 1 hits
3 NPHS1 1 hits
4 NPHS2 1 hits
5 PIK3CA 1 hits

Related Sentences

# PMID Sentence
1 12832477 We demonstrate that both nephrin and CD2AP interact with the p85 regulatory subunit of phosphoinositide 3-OH kinase (PI3K) in vivo, recruit PI3K to the plasma membrane, and, together with podocin, stimulate PI3K-dependent AKT signaling in podocytes.
2 19679673 We found that the C-terminal region of CD2AP interacts directly with the cytoplasmic tail of the TGF-beta receptor type I (TbetaRI) in a kinase-dependent manner and that the interaction between the TbetaRI and the p85 subunit of PI3K requires CD2AP.
3 20472933 This Nephrin-induced cofilin activation required a direct interaction between Nephrin and the p85 subunit of phosphatidylinositol 3-kinase.