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Gene Information
Gene symbol: SGK1
Gene name: serum/glucocorticoid regulated kinase 1
HGNC ID: 10810
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | NOX5 | 1 hits |
| 2 | NPHS1 | 1 hits |
| 3 | SOD1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21220752 | In cultured MR-expressing podocytes, high glucose significantly enhanced Sgk1 expression, activated nicotinamide adenine dinucleotide phosphate (NADPH) oxidase and ROS production and induced podocyte apoptosis. |
| 2 | 21695412 | The activation of Src-family kinases was correlated with nephrin phosphorylation, both of which were abolished by small interfering RNA (siRNA) treatment for serum/glucocorticoid-induced kinase 1 (SGK1). |
| 3 | 21695412 | These results clarify a novel action of glucocorticoid on nephrin phosphorylation through SGK1. |
| 4 | 17200434 | In addition, proteinuria, podocyte damage, and Sgk1 upregulation were significantly alleviated by tempol, a membrane-permeable superoxide dismutase, suggesting the pathogenic role of oxidative stress. |