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Gene Information

Gene symbol: VDR

Gene name: vitamin D (1,25- dihydroxyvitamin D3) receptor

HGNC ID: 12679

Synonyms: NR1I1

Related Genes

# Gene Symbol Number of hits
1 AGT 1 hits
2 CD74 1 hits
3 MED1 1 hits
4 NPHS1 1 hits
5 NR3C2 1 hits
6 RARA 1 hits
7 TNF 1 hits

Related Sentences

# PMID Sentence
1 19474283 ATRA-triggered, RAR-mediated activation of the nephrin gene promoter was not suppressed by the VDR antagonist.
2 19474283 In contrast, the 1,25(OH)(2)D(3)-triggered, VDR-mediated activation of the nephrin gene promoter was significantly suppressed by the RAR antagonist, but not by RXR antagonists.
3 21209008 Furthermore, the VDR agonist also prevents the activation of the renin-angiotensin-aldosterone system including the angiotensin II type 1 receptor and the mineralocorticoid receptor.
4 20237236 We previously reported that 1) expression of nephrin in cultured podocytes is reinforced by retinoic acid (RA) and 1,25-dihydroxyvitamin D(3), 2) these effects are mediated by retinoic acid receptor (RAR) and vitamin D receptor (VDR), and 3) basal and inducible expression of nephrin is downregulated by TNF-alpha.
5 20504837 Vitamin D receptor activation with paricalcitol or calcitriol prevented the increase in TGF-?1, CD74 and extracellular matrix induced by lyso-Gb3.
6 21803771 ChIP assays showed that, upon 1,25(OH)(2)D(3) activation, VDR bound to this VDRE leading to recruitment of DRIP205 and RNA polymerase II and histone 4 acetylation.