Ignet

Gene Pair: CD28, CD86

Related Sentences

#	PMID	Sentence
1	11120800	CD28, the primary positive costimulatory receptor on T cells, has two identified ligands, B7-1 and B7-2.
2	11120800	Functional differences between B7-1 and B7-2 observed in vivo therefore may not reflect inherent differences in the interactions of CD28 with these ligands.
3	15353589	Taken together, these results strongly suggest that CD26-caveolin-1 interaction plays a role in the up-regulation of CD86 on TT-loaded monocytes and subsequent engagement with CD28 on T cells, leading to antigen-specific T cell activation.
4	16982886	Previous studies have suggested that CD80 binding to CD28 may be superior to CD86 for the activation of naive CD8+ T cells.
5	17629370	The importance of CD28 (CD86 ligand) was confirmed using CD28 deficient mice which presented severely impaired immune responses following CpG ODN-assisted immunization.