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Gene Pair Information
Gene Pair: CD28, NFKB1
Related Sentences
# |
PMID |
Sentence |
1 |
19017952
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CD28-mediated signaling through PI3K results in the recruitment of protein kinase C-theta (PKCtheta) to the cSMAC, activation of NF-kappaB, and up-regulation of IL-2 transcription.
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2 |
19017952
|
Mutation of tyrosine 188 also results in diminished activation of NF-kappaB, suggesting that CD28-mediated localization of PKCtheta to the cSMAC is important for efficient signal transduction.
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