Ignet

Gene Pair Information

Gene Pair: CD4, IL17A

Related Sentences

#	PMID	Sentence
1	17505023	Cross-talk between TGF-beta and IL-6 has been shown to direct the differentiation of CD4(+) cells into special IL-17-secreting cells, which are termed Th17 cells.
2	17719276	In this review, we present evidence that suggests memory CD4(+) T cells can protect against tuberculosis in the absence of interferon gamma, and discuss potential mechanisms that may be involved such as IL-17 and regulatory T cells.
3	20484570	Preexisting immune responses to mycobacterial antigens were associated with higher CD4(+) CD25(hi) CD39(+) T-cell levels in the periphery and a reduced capacity to produce IL-17A following immunization.
4	21095257	In contrast, CD8+ T cells produced relatively little IFN-? but more IL-17 than the CD4 compartment.
5	21236236	Also, CD4(+) cells at the dLN from the mice expressed prominent interferon-?, but not IL-4 or IL-17, mRNA at a maximum level at day 5 following vaccination.
6	18209095	Remarkably, >20% of specific cytokine-producing CD4(+) T cells in peripheral blood of healthy, mycobacteria-exposed adults expressed IL-17 or IL-22.
7	21715555	Elevated type 1 diabetes CD4+CD25+ cell proliferation correlated with increased inflammatory cytokines interleukin 17 and tumor necrosis factor-? but not ?-interferon.
8	21791667	Significantly reduced percentages of functional CD45RA(Low) memory CD4(+) T cells producing specific cytokines (interferon ?, interleukin [IL]-2, IL-4 and IL-17a) were observed in otitis-prone children following AOM and NP colonization with either S. pneumoniae or H. influenzae.
9	22102924	However, little in vivo data are available on the dynamics of Th17 cells, another important CD4(+) T cell subset, after Schistosoma japonicum infection or whether these cells and their defining IL-17 cytokine mediate host protective responses early in infection.