Ignet

Gene Pair: IL2, CD28

Related Sentences

#	PMID	Sentence
1	1717561	Together, these results suggest that the two signals required for IL-2 production by CD4+ T cells can be transduced by the TCR and CD28.
2	16301632	However, only CD28 signals enabled target T cells to resist the early Treg-induced down-regulation of IL-2.
3	19483649	Using this model, we found that induction of lymphopenia before adoptive transfer of ex vivo anti-CD3/CD28 activated and interleukin-2 expanded D5-G6 tumor draining lymph node cells enhanced the antitumor efficacy of the infused cells in both pulmonary metastases and subcutaneous D5 bearing mice.
4	20029165	CD45RO+/KLRG1+/CD57+/CD28-), enhanced IL-2 production and T-lymphocyte expression of the IL-2 receptor, longer chromosome telomere lengths in blood leukocytes and in vivo immune responses to vaccines and recall antigens.
5	22025707	CD28 signaling is known to abrogate Treg suppression of IL-2 secretion and proliferation, but our studies show that Treg suppression of IFN-? during Th1 priming proceeds despite enhanced CD28 signaling.