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Gene Pair Information
Gene Pair: PSEN1, APLP2
Related Sentences
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PMID |
Sentence |
1 |
12230303
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Some cases of AD are caused by mutations in presenilin-1 (PS1), and it has been shown that PS1 mutations perturb neuronal calcium homeostasis, promote increased production of amyloid beta-peptide (Abeta), and render neurons vulnerable to synaptic dysfunction, excitotoxicity, and apoptosis.
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