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Gene Pair Information
Gene Pair: RB1, TP53
Related Sentences
# |
PMID |
Sentence |
1 |
16969092
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To do so, virus products must interfere not only with the basal cell cycle regulators, such as pRb or Mad2, but also with the main surveillance pathways such as those controlled by p53 and ATM.
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2 |
19846973
|
Sixteen tumours showed altered p53 expression, while 14 showed altered pRb expression.
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3 |
19177752
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The E6 and E7 genes of HPVs are thought to play causative roles, since E6 promotes the degradation of p53 through its interaction with E6AP, an E3 ubiquitin ligase, whereas E7 binds to the retinoblastoma protein pRb and disrupts its complex formation with E2F transcription factors.
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