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Gene Pair Information
Gene Pair: RIPK1, ZBP1
Related Sentences
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PMID |
Sentence |
1 |
18941233
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In this study, induction of NF-kappaB is shown to depend on the adaptor receptor-interacting protein kinase (RIP)1, acting via a RIP homotypic interaction motif (RHIM)-dependent interaction with DAI.
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2 |
18941233
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DAI binds to and colocalizes with endogenous RIP1 at characteristic cytoplasmic granules.
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3 |
18941233
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The role of DAI in activation of NF-kappaB in response to immunostimulatory DNA appears to be analogous to sensing of dsRNA by TLR3 in that both pathways involve RHIM-dependent signaling that is mediated via RIP1, reinforcing a central role for this adaptor in innate sensing of intracellular microbes.
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