Ignet

Gene Pair: SPG7, MAPK8

Related Sentences

#	PMID	Sentence
1	21450974	PGN stimulates the activation of all three classes of MAPKs, extracellular signal-related kinase (ERK), c-Jun N-terminal kinase (JNK), and p38(mapk) in macrophages, albeit with differential activation kinetics.
2	21450974	Using a selective inhibitor of JNK (SP600125) and JNK1/2 small interfering RNA (siRNA) knocked-down macrophages, it was observed that PGN-induced iNOS and NO expression is significantly inhibited.
3	21450974	This suggested that JNK MAPK plays an essential role in PGN-induced iNOS expression and NO production.