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Gene Pair Information
Gene Pair: TBX21, CD4
Related Sentences
# |
PMID |
Sentence |
1 |
16188982
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The transcription factor T-bet regulates the differentiation of CD4(+) T-helper type 1 (Th1) cells and represses Th2 lineage commitment.
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2 |
21642544
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In naive CD4 T cells, IFN-? production only occurred after sustained Ag activation and was associated with high expression of the T-bet transcription factor required for Th1 differentiation and with T-bet binding to the IFN-? promoter as assessed by chromatin immunoprecipitation analysis.
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3 |
21642544
|
By contrast, immediate IFN-? production by Ag-stimulated memory CD4 T cells occurred in the absence of significant nuclear T-bet expression or T-bet engagement on the IFN-? promoter.
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