Ignet

Gene Pair: ZBP1, RIPK1

Related Sentences

#	PMID	Sentence
1	18941233	In this study, induction of NF-kappaB is shown to depend on the adaptor receptor-interacting protein kinase (RIP)1, acting via a RIP homotypic interaction motif (RHIM)-dependent interaction with DAI.
2	18941233	DAI binds to and colocalizes with endogenous RIP1 at characteristic cytoplasmic granules.
3	18941233	The role of DAI in activation of NF-kappaB in response to immunostimulatory DNA appears to be analogous to sensing of dsRNA by TLR3 in that both pathways involve RHIM-dependent signaling that is mediated via RIP1, reinforcing a central role for this adaptor in innate sensing of intracellular microbes.