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Gene Pair Information
Gene Pair: ADIPOQ, TXNDC4
Related Sentences
# |
PMID |
Sentence |
1 |
18177270
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Secretion of the adiponectin oligomers is tightly controlled by a pair of molecular chaperones in the ER (endoplasmic reticulum), including ERp44 (ER protein of 44 kDa) and Ero1-Lalpha (ER oxidoreductase 1-Lalpha).
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2 |
19622782
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Expression of the chaperone protein ERp44, which retains adiponectin within the cell, was decreased by TZD treatment.
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3 |
19622782
|
Finally, TZDs promote the selective secretion of HMW adiponectin, potentially, in part, through decreasing the expression of the adiponectin-retaining protein ERp44.
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4 |
20484463
|
In human embryonic kidney 293 cells stably transfected with cDNA encoding porcine adiponectin, the secretion of adiponectin was significantly up-regulated and the ERp44 mRNA was down-regulated observably, by either the treatment of PPARgamma agonist rosiglitazone or the overexpression of PPARgamma in these cells.
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5 |
20484463
|
Taken together, our results indicated that PPARgamma is an essential regulatory factor for the transcriptional activity of ERp44, which in turn controls the secretion of adiponectin.
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