Ignet

Gene Pair: AGT, MMP9

Related Sentences

#	PMID	Sentence
1	20666722	Angiotensin II induces gene expressions of transforming growth factor (TGF)-? and matrix metalloproteinase (MMP)-9, and chymase also converts precursors of TGF-? and MMP-9 to their active forms.
2	20666722	In this model, the AAA development on an increase in MMP-9 activities induced by angiotensin II, but the inhibition of MMP-9 activation by chymase inhibitor resulted in attenuation of the AAA development.
3	20666722	Therefore, chymase inhibition may be useful for attenuating MMP-9 and TGF-? levels, in addition to reducing angiotensin II formation, and this function may provide powerful preventions of organ damages.