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Gene Pair Information
Gene Pair: APLP2, GPLD1
Related Sentences
# |
PMID |
Sentence |
1 |
15259000
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Since GPI-PLD is synthesized by, and secreted from, pancreatic islet beta cells, the present study examined the hypothesis that GPI-PLD associates with islet amyloid.
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2 |
15259000
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Heparan sulphate proteoglycan, which is commonly present in most amyloid, bound GPI-PLD in vitro.
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3 |
15259000
|
GPI-PLD inhibited the formation of amyloid fibrils from synthetic islet amyloid polypeptide in vitro.
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4 |
15259000
|
Since GPI-PLD also inhibited islet amyloid polypeptide fibril formation in vitro, it is concluded that GPI-PLD may play a role in islet amyloid formation in type 2 diabetes.
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