Ignet

Gene Pair: APLP2, INSR

Related Sentences

#	PMID	Sentence
1	7677175	We have previously demonstrated that IAPP-derived amyloid forms intracellularly in humans with chronic excess insulin expression (eg, insulinoma and insulin receptor antibody-induced insulin resistance).
2	15750215	These abnormalities were associated with reduced levels of insulin receptor substrate (IRS) mRNA, tau mRNA, IRS-associated phosphotidylinositol 3-kinase, and phospho-Akt (activated), and increased glycogen synthase kinase-3beta activity and amyloid precursor protein mRNA expression.
3	16444902	Such a decrease involves the insulin receptor cascade and can also increase amyloid toxicity.