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Gene Pair Information
Gene Pair: BBS2, LEPR
Related Sentences
| # | PMID | Sentence |
| 1 | 19150989 | Here, we show that BBS proteins are required for leptin receptor (LepR) signaling in the hypothalamus. |
| 2 | 19150989 | In contrast, downstream melanocortin receptor signaling is unaffected, indicating that LepR signaling is specifically impaired in Bbs2(-/-), Bbs4(-/-) and Bbs6(-/-) mice. |
| 3 | 19150989 | Furthermore, we found that BBS1 protein physically interacts with the LepR and that loss of BBS proteins perturbs LepR trafficking. |