Ignet

Gene Pair: CASP3, MAP3K5

Related Sentences

#	PMID	Sentence
1	19959470	In mitochondria, TXNIP binds to and oxidizes Trx2, thereby reducing Trx2 binding to ASK1 and allowing for ASK1 phosphorylation/activation, resulting in induction of the mitochondrial pathway of apoptosis with cytochrome c release and caspase-3 cleavage.