Ignet

Gene Pair: CDC73, MYC

Related Sentences

#	PMID	Sentence
1	18987311	We show here that RNA interference with the expression of parafibromin or Paf1 stimulates cell proliferation and increases levels of the c-myc proto-oncogene product, a DNA-binding protein and established regulator of cell growth.
2	18987311	Knockdown of c-myc blocks the proliferative effect of RNA interference with parafibromin or Paf1 expression.
3	18987311	These experiments provide a previously uncharacterized mechanism for the anti-proliferative action of the parafibromin tumor suppressor protein resulting from PAF1 complex-mediated inhibition of the c-myc proto-oncogene.