Ignet

Gene Pair: COL1A1, CCL2

Related Sentences

#	PMID	Sentence
1	20980457	Although overexpression of renal Smad7 had no effect on levels of blood glucose, it significantly attenuated the development of microalbuminuria, TGF-?/Smad3-mediated renal fibrosis such as collagen I and IV and fibronectin accumulation and NF-?B/p65-driven renal inflammation including IL-1?, TNF-?, MCP-1, and ICAM-1 expression and macrophage infiltration in diabetic rats.
2	21169360	In human mesangial cells (a microvascular pericyte that secretes excess collagen in diabetic glomerulosclerosis), ET-1 increased mRNA and protein for MCP-1 (macrophage chemoattractant protein-1) and IL-6.
3	21169360	Neither an MCP-1-neutralizing antibody nor an MCP-1 receptor antagonist inhibited ET-1-induced collagen accumulation.