Ignet

Gene Pair: COL1A1, PRKCA

Related Sentences

#	PMID	Sentence
1	10967557	Taken together, our results demonstrate that osteoblasts respond to increasing extracellular glucose concentration through an osmotic response pathway that is dependent upon protein kinase C activity and results in upregulation of c-jun and modulation of collagen I and osteocalcin expression.
2	17728702	In contrast, 8-week exposure to HG resulted in the persistent activation of PKC-delta, did not change PKC-alpha or -beta activity, and decreased PKC-epsilon activity while increasing collagen I and IV gene and protein expression.
3	21456600	PCA treatments also dose-dependently decreased the renal level of type-IV collagen, fibronectin, and transforming growth factor-?1 (p < 0.05), as well as dose-dependently diminished renal protein kinase C (PKC) activity (p < 0.05); however, PCA treatments only at 4% suppressed renal mRNA expression of PKC-? and PKC-beta (p < 0.05).