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Gene Pair Information
Gene Pair: CREBBP, INS
Related Sentences
# |
PMID |
Sentence |
1 |
15590659
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These data suggest that insulin inhibits glucagon gene transcription by signaling via PI 3-kinase and PKB, with the transcription factor Pax6 and its potential coactivator CBP being critical components of the targeted promoter-specific nucleoprotein complex.
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2 |
19450513
|
Mice carrying a germline mutation of this CBP phosphorylation site (S436A) demonstrate resistance to the hypoglycemic effect of both insulin and metformin.
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