Ignet

Gene Pair: FASN, SNF1LK2

Related Sentences

#	PMID	Sentence
1	18239551	Electroporation was used to transiently transfect 3T3-L1 adipocytes with fatty acid synthase (FAS) promoter-driven luciferase construct to evaluate the effect of SIK2 on FAS transcription.
2	18239551	Overexpression of SIK2 repressed the expression of lipogenic genes, including FAS, acetyl CoA carboxylase 2 (ACC2), and stearoyl CoA desaturase 1 (SCD1), and reduced triglyceride content.
3	18239551	Reduction of endogenous SIK2 expression through RNA interference increased the expression of FAS, ACC2, and SCD1.
4	18239551	SIK2 inhibits the expression of FAS-promoter driven luciferase reporter gene, and this effect can be reversed by overexpression of constitutively active sterol regulatory element binding protein-1 (SREBP-1).