Ignet

Gene Pair: GCG, CDX2

Related Sentences

#	PMID	Sentence
1	21691557	From a potential Cdx-2 interaction protein identified, we examined its expression in pancreatic and gut endocrine cells, confirmed its interaction with Cdx-2 by GST-pull down and determined its effect in provoking Gcg expression in cell lines that do not express endogenous Gcg.
2	21691557	Finally, when Cdx-2 and Nkx6.2 were co-transfected into the undifferentiated rat intestinal IEC-6 cell line, it produced detectable amount of Gcg mRNA.
3	21691557	Cdx-2 recruits Nkx6.2 in exerting its effect in stimulating Gcg expression.
4	21691557	Our observations further support the notion that multiple HD proteins, including Cdx-2 and Nkx6.2, are involved in the regulation of Gcg expression and the genesis of Gcg-producing cells.